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wolfberry extract !!!!!!!!!!

Brand Name:
wolfberry extract !!!!!!!!!!
Detailed Description

Types: Chinese wolfberry
Chinese pinyin: gou qi
English name: Barbary Wolfberry Fruit, Fruit of Barbary Wolfberry, Fruit of Ma

Pharmacology wolfberry 1, the influence of the immune function:
Medlar polysaccharide on 3 H a TdR mixed with mice splenic lymphocytes and Ts cells impact:
To 3 H a TdR mixed people splenic lymphocytes impact:
LBP (LBP) 5 mg/kg and 10 mg/kg. Day) by seven days, intraperitoneal injection can obviously increase ConA entrainment under 3 H a TdR mixed with spleen T cells value, 10 mg/kg can make mixed with index peak, three times higher than the control group. And LBP25mg/kg and 50 mg/kg of spleen T cells transform reaction had significant inhibitory effect. Show to LBP spleen T lymphocyte proliferation effect and that there is a close relationship between doses. To LBP improve spleen T lymphocyte transformation value the most significant doses of 10 mg/kg. Day) by seven days, observe the B lymphocytes mitotic agent LPS induction 3 H a TdR mixed with cells effect. In the concentration of 50.70 and 100 LPS μ g/ml, LBP to 3 H a TdR mixed with B cells was no significant effect on the B cells that LBP mitosis agent of cell transformation induced function is not sensitive.
Antibody formation of spleen cells the role of number:
LBP in 5.20 mg/kg. Day) by seven days can significantly higher number of PFC spleen, 5 mg/kg doses can make several normal immune control group of PFC 1.4 times. And 25.50 mg/kg, the number of PFC see reduced significantly, and among them 25 mg/kg group normal number of PFC 43% of the control group. Show of antibody formation cell count LBP the enhancement effect has the right dose.
To the influence of the function of spleen Ts cells:
Using the right amount SRBC immune silicon-on-insulator (SOI) induced Ts cells observed method, donor cells in mice splenic cell Ts can make normal immune suppression of the number of PFC mice by 63%, the results show that the method can induce SOI of antibody generating cells to produce significant inhibitory effect of Ts cells. Give donor rat LBP5mg / (kg. Day) x 7 days, receptor rat than control group number SOI PFC dropped significantly, indicating that this dose of Ts cell function have enhanced role. As the dosage increased to 25, 50 mg/kg, LBP for Ts cells enhancement obviously decline.
Medlar polysaccharide on S180 tumor-burdened mouse cell immune function and its inhibitory effect of role:
Medlar polysaccharide on the normal mice cellular immune function impact:
Mice LBP5mg intraperitoneal injection / (kg. Day), continuous 7 days (do-6), in the seventh day take the spleen T lymphocyte proliferation measured response. The results show that LBP can obviously increase the normal mice induced by the ConA the spleen T lymphocyte proliferation reaction, the value of the CPM group 28410 + 3110 to improve the treatment group 64870 + 2571.
Medlar polysaccharide on S180 tumor-burdened mouse cell immune function and its inhibitory effect of role: subcutaneous tumor cells in mice inoculated S180 after 2 days, LBP10mg intraperitoneal injection or 20 mg/kg. Day) x 7 day, 9 days put to death in mice, the tumor weight and spleen T lymphocyte proliferation reaction. The results show that LBP10mg and 20 mg/kg YiLiuLv of 31% and 39% respectively. Note also LBP10mg mice T lymphocyte proliferation reaction by not giving medicine is CPM group 139 + 62 to improve the treatment group 5581 + 783, RPI (Relative roliferationinde ×, Relative proliferation index) is equivalent to 0.3% of normal increase from 24.6% to. Experiment with cyclophosphamide (Cy) do the positive control, one subcutaneous injection 25 mg/kg, YiLiuLv for 47%, T lymphocyte proliferation reaction CMP value for 165 + 31.

Chinese wolfberry medlar polysaccharide by cyclophosphamide inhibition to the normal mice cellular immune function impact: mice in subcutaneous injection Cy25mg/kg intraperitoneal injection began on the same day LBP5mg / (kg. Day) x 7 days, in the seventh day take measure T cell proliferation spleen reaction. Results after 105% RPI plus LBP (single Cy mice with the normal RPI 33%), the results show that the fight against the Cy LBP completely by the cellular immune function of the low effect.
Medlar polysaccharide and cyclophosphamide share the antimicrobial effect of:
S180 cells in mice subcutaneous inoculation two days after subcutaneous injection Cy25mg/kg, YiLiuLv for 31%, while intraperitoneal injection LBP 10 m / (kg. Day) by seven days, the YiLiuLv increased from 47% to, but no significant difference (P > 0.05). When l2.5 Cy subcutaneous injection mg/kg YiLiuLv when is 14%, the tumors and the tumor heavy compared had no significant difference, such as also share LBP10mg / (kg. Day) by seven days, intraperitoneal injection is YiLiuLv to 54%, (P < 0.01), show that can enhance the antimicrobial LBP Cy tumor role.
Medlar polysaccharides and combined application anaerobic bacteria in mice JunMiao short great abdominal macrophage proliferation activity suppress tumor influence:
Medlar polysaccharide in normal mice to intraperitoneal injection 40 mg/kg. Day) by seven days can enhance the ConA processing of macrophages inhibit tumor cell proliferation activity target; LBP5, 10, 20, 40 mg/kg. Day) by seven days and with small dose (250 ug/only) anaerobic short great coli JunMiao (CorynebacteriumParvum, CP) combined application has obvious synergy effect. The concentration of 20 in LBP mg/kg, effect in the most significant, and to the target cells P815 and P388 proliferation, the inhibition rate to 85.5% and 63.6%, respectively; CP control group were 28.1% and 24. O %. That application LBP and merger can reduce the dosage of both CP, enhance effect, reduce the side effects of CP. LBP T cells in the role of main immune strength agent, can enhance CTL, NK cell function; CP is macrophages stimulants. Experiments show that, combined application effect in different stages of the immune response immunity enhancement agent can get synergy effect. The experiment also showed that no matter to LBP macrophages in the specificity anti-tumor or specificity anti-tumor process all has

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